Rossjohn Laboratory

Understanding immune function and dysfunction.

Our Members

Prof. Jamie Rossjohn
FAA FAHMS FLSW FMedSci

Professor Jamie Rossjohn’s research is centered on an understanding immunity. He is currently an ARC Australian Laureate Fellow (2017-2021) and previously a NHMRC Australia Fellow (2011-2016) and ARC Federation Fellow (2007-11). He is the Head of the Infection and Immunity Program of the Biomedicine Discovery Institute. Prof. Rossjohn is known for his contributions to the understanding the molecular basis underpinning immunity. He has used structural biology to explain pre-T- cell receptor (TCR) self-association in T-cell development, and how the TCR specifically recognises polymorphic Human Leukocyte Antigen (HLA) molecules in the context of viral immunity and aberrant T- cell reactivity.

He has unearthed structural mechanisms of HLA polymorphism impacting on drug and food hypersensitivities, as well as Natural Killer cell receptor recognition. He has pioneered our molecular understanding of lipid-based immunity by T cells, revealing that it can differ fundamentally from peptide-mediated adaptive immunity.

Recently he has provided a structural basis of how vitamin B metabolites can be presented and recognised by the immune system, revealing a new class of antigen. Collectively, he has published > 300 papers and mentored numerous researchers towards obtaining higher degrees and nationally competitive fellowships.

Major Fellowships

  • 1995 Royal Society Postdoctoral Fellowship.
  • 1998 Australian Research Council Postdoctoral Fellowship (3 years).
  • 2000 R.D. Wright NHMRC Research Fellowship (4 years).
  • 2001 Wellcome Trust International Senior Research Fellowship in Biomedical Science.
  • 2006 Australian Research Council Professorial Fellowship.
  • 2006 Australian Research Council Federation Fellowship.
  • 2011 NHMRC Australia Fellowship.
  • 2014 Elected as a Fellow into the Australian Academy of Science.
  • 2015 Elected as a Fellow into the Learned Society of Wales.
  • 2016 ARC Australian Laureate Fellowship.
  • 2017 Elected as a Fellow into the Academy of Medical Sciences.
  • 2017 Elected as a Fellow into the Australian Academy of Health and Medical Sciences.

Awards

  • 2001 Ramaciotti New Investigator Award.
  • 2003 Australian Society of Biochemistry and Molecular Biology (ASBMB) Roche medallist.
  • 2004 Science Ministers Prize: Life Scientist of the Year.
  • 2007 Australian Academy of Science Gottschalk medal.
  • 2007 Commonwealth Health Ministers Award for Excellence in Health and Medical Research.
  • 2011 Roche Organ Transplantation Research Foundation Recognition Prize (jointly with Prof. McCluskey).
  • 2011 Australian Museum – Eureka Finalist for Infectious Diseases Research (jointly with A/Prof. Beddoe & Prof. Paton).
  • 2011 NHMRC Recognition Award for the Top ranked Program Grant in 2010.
  • 2012 Ramaciotti Biomedical Research Award (jointly with Profs. Whisstock, Smith & Lawrence).
  • 2013 Leiden University Medical Centre Boerhaave Medal.
  • 2013 Australian Museum – University of New South Wales Eureka Prize for Scientific Research (jointly with Dr. Kjer-Nielsen & Prof. McCluskey).
  • 2014 NHMRC Research Excellence Award for the Top ranked Project Grant in 2013.
  • 2015 GSK Research excellence (jointly with McCluskey)
  • 2016 Victoria Prize for Science and Innovation (jointly with McCluskey)
  • 2017 Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB) Award for Research Excellence 2017 (presented at ConBio/FAOBMB meeting, Kobe, Japan Dec 2017).

Group Leaders

Dr Hugh Reid
Senior Research Fellow
Dr Jerome Le Nours
ARC Future Fellow
Dr Julian Vivian
Senior Research Fellow
Dr Richard Berry
NHMRC Career Development Fellow
Associate Professor Stephanie Gras
Monash Senior Research Fellow

Personnel

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Alumni

  • Dr. Michelle Dunstone
  • Dr. Judith Scoble
  • Dr. Emma Byres
  • Dr. Emma Hopkins
  • Dr. Trevor Huyton
  • Dr. Natalie Borg
  • Dr. Tongted Das
  • Dr. Bo Baker
  • Dr. Mark Walter
  • Dr. Versha Rai
  • Dr. Isabelle Lucet
  • Dr. Kevin Ge
  • Dr. Julia Archbold
  • Dr. Adrian McAlister
  • Dr. Siew Siew Pang
  • Dr. Jobichen Chako
  • Dr. Andrew Welland
  • Dr. Laila Roisman
  • Dr. Renee Duncan
  • Dr. Pascal Wilmann
  • Dr. Trifina Sofian
  • Dr. Kelly-Anne Twist
  • Dr. Kelly Winter
  • Dr. Sara Baratchi
  • Dr. Thao Nguyen
  • Dr. Peter Vella
  • Dr. Craig Clements
  • Dr. Alex Theodossis
  • Dr. Mugdha Bhati
  • Dr. Natasha Ng
  • Dr. Matthew Johnson
  • Dr. Onisha Patel
  • Dr. Richard Birkinshaw
  • Dr Claudia Del Campo
  • A/Prof. Travis Beddoe
  • Dr Tracey Josephs
  • Dr Alexander Rey
  • Dr Andrew Keller
  • Dr Tang Yongqing
  • Geoffrey Williams
  • Kent Cheng
  • Pascal Wilmann
  • Zara Marland
  • Simon Bushell
  • Kate Henderson
  • Fleur Tynan
  • Hilary Hoare
  • Nicole Drentin
  • Alice Xu
  • Robb Wesselingh
  • Lynn Tan
  • Joshua Hayward
  • Melissa McKnight
  • Sophie Broughton
  • Nicholas Walpole
  • Li Zheng
  • Andrew Clarke
  • Amelia Aslanides
  • Gautham Balaji
  • John Liu
  • Rhys Pryce
  • Stephen Scally
  • Naomi Richardson
  • Virginia Richichi
  • Kelly Hibbert
  • Rachael Woolley
  • Leyla Zaker-Tabrizi
  • Cathleena McLaren
  • Patricia Walden
  • Rebecca Bamert
  • Maya Olshina
  • Ruide Koh
  • Andrew Gibb
  • Tara Wong
  • Danuta Maskel
  • Sally Troy
  • Susan Reynolds
  • Kristy Campbell
  • Lynn Tan
  • Margaret Bills
  • Dr. Whitney Macdonald
  • Sofia Mahood-Ul-Hassen
  • Dr. Andrew Sivakumaran
  • Nor Abdul Hasmaliana Manas
  • Noor Haza Fazlin Hashim
  • Tanya Bashtannyk-Puhalovich